Clinical Toxicology
When numbers can be misleading: lithium induced irreversible neurotoxicity at therapeutic drug levels

Jyoti Aggarwal; Zainab Mehdi; Baldeep Kaur; Yuvraj Singh Cheema; Monica Gupta

Volume 8, Issue 1 , January 2022, , Pages 69-73

  Objective: Lithium is a principal drug used in the treatment of bipolar disorder (BPD). Due to its narrow therapeutic index, serum levels need to be monitored regularly. In elderly patients with renal dysfunction lithium toxicity can develop paradoxically within the therapeutic range. This can lead to ...  Read More