Clinical Toxicology
Zohreh Oghabian; Maral Ramezani; Shahin Shadnia; Farah Pouramiri; Babak Mostafazadeh; Masoomeh Varzandeh; Peyman Erfan Talab Evini; Shahrad Tajaddini; Mitra Rahimi
Volume 10, Issue 1 , January 2024, , Pages 82-87
Abstract
Objective: Paraquat poisoning is a critical condition with a high mortality rate, and there are currently no established treatment guidelines for managing this toxin. Hemoperfusion constitutes an alternative treatment for paraquat poisoning. This study aimed to evaluate the efficacy of hemoperfusion ...
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Objective: Paraquat poisoning is a critical condition with a high mortality rate, and there are currently no established treatment guidelines for managing this toxin. Hemoperfusion constitutes an alternative treatment for paraquat poisoning. This study aimed to evaluate the efficacy of hemoperfusion therapy using the Jafron HA330 hemoperfusion cartridge in patients with paraquat poisoning.Case Presentations: This case series study was conducted on paraquat poisoning patients in Tehran’s Loghman Hakim and Kerman’s Afzalipour hospitals. In addition to the standard treatment of poisoning patients, the patients underwent hemoperfusion using the HA330 cartridge three times at 24-hour intervals, each time lasting 180–240 minutes. Before and following the completion of the treatment program, patients’ information and laboratory results were meticulously documented. Statistical analysis was performed using SPSS software version 21. The study noted that eight of the nine patients passed away. A notable finding was the significant reduction in potassium levels in the blood. Seven patients required intubation. A notable reduction in hemoglobin levels was detected following treatment. Furthermore, a decline in bicarbonate and pH levels was observed in patients, in post-treatment, though this decrease did not attain statistical significance. Conversely, the total bilirubin levels exhibited an increase in patients following treatment; however, this change was not statistically significant.Conclusion: The findings of this study suggest that hemoperfusion with HA330 cartridges does not yield a substantial improvement in the survival of patients poisoned by paraquat.
Clinical Toxicology
Rouhullah Dehghani; Shahrad Tajaddini; masoomeh varzandeh
Volume 9, Issue 2 , July 2023, , Pages 81-86
Abstract
Objective: Arthropod bites and stings have always been of interest to humans; therefore, researchers have always been interested in their prevention and timely treatment. Considering the brilliance of ancient Iranian physicians, especially Avicenna, this study was conducted based on their views on diagnosing ...
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Objective: Arthropod bites and stings have always been of interest to humans; therefore, researchers have always been interested in their prevention and timely treatment. Considering the brilliance of ancient Iranian physicians, especially Avicenna, this study was conducted based on their views on diagnosing and treating venomous arthropod bites and stings.Methods: This study is a narrative review conducted by surveying sources, especially The Canon of Medicine, and searching for the keywords “bites,” “stings,” “poisonous,” “venomous arachnids,” and“insects” as well as the diagnosis and treatment of bites and stings .The study was conducted in 2022 and in Kashan and Kerman universities of medical sciences. Sampling method was based onthe study objective.The collected data was then summarized.Results: To diagnose the bite or sting, the clinical manifestations of the patient, local symptoms in the bite or sting site, and the classification of the venomous arthropods, such as spiders, wasps, scorpions, etc., are used. Venom suction and using medicinal plants and ointments of mineral compounds were proposed as treatment methods.Conclusion: Therapeutic methods and the use of herbal and mineral compounds are widely mentioned in The Canon. There are a lot of connections and harmony between modern and conventional medicine, in the clinical description of bites and stings as well as their diagnosis, but more research is suggested on treatment methods
Clinical Toxicology
Rouhullah Dehghani; Nasrullah Rastegar Pouyani; Shahrad Tajaddini; Masoomeh Varzandeh
Volume 8, Issue 2 , July 2022, , Pages 162-165
Abstract
Objective: Snakes are among the predators of any ecosystem and have been seen in different parts of Iran. The report on their distribution in Isfahan province was taken into consideration because of the importance of regional knowledge of these animals.Case report: During this survey, a sample of snakes ...
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Objective: Snakes are among the predators of any ecosystem and have been seen in different parts of Iran. The report on their distribution in Isfahan province was taken into consideration because of the importance of regional knowledge of these animals.Case report: During this survey, a sample of snakes was collected from north of Isfahan province, Kashan city, the University site of Medical Sciences and the sample was studied. The snake was identified by morphological and habitat characteristics and compared to other photos and data. The specimen belonged to the Colubridae family and non-venomous snakes. This species is distributed in the tropical climatic zone of the province. The species of the tropical region of Kashan city was identified as Platyceps karelini. or spotted snakeConclusion: We identified the habitat of this animal in Kashan city in Isfahan province. By identifying the species of Spotted Desert Racer from the Colubridae family, the number of non-venomous snakes in Kashan reached eight species.