Document Type : Case Report

Authors

1 Department of Emergency Medicine, Medipol University Hospital, İstanbul, Turkey

2 Department of Emergency Medicine, Gaziemir State Hospital, Izmir, Turkey

Abstract

 Statins are commonly used drugs in the treatment of hyperlipidemia (HL), despite some undesirable side effects. These range from mild symptoms such as myopathy, muscle weakness and myalgia to severe muscle weakness associated with chronic myopathy and acute renal failure (ARF) as a result of rhabdomyolysis. The most serious and deadly side effect of statins is rhabdomyolysis. The case presented here is of a patient with rhabdomyolysis due to treatment with the antihyperlipidemic drug, atorvastatin.

Keywords

Main Subjects

 1. Yılmaz G, Çavuş T, Çakır H, Narlı E. Fibrat kullanımına bağlı rabdomiyoliz gelişimi ile ilişkili akut böbrek yetersizliği. Journal of Istanbul Faculty of Medicine 2011; 74(1): 13-14. [in Turkey].
2. Hansen KE, Hildebrand JP, Ferguson EE, Stein JH. Outcomes in 45 patients with statin-associated myopathy. Arch Intern Med 2005; 165(22): 2671-6. doi: 10.1001/archinte.165.22.2671.
3. Pasternak RC, Smith SC Jr, Bairey-Merz CN, Grundy SM, Cleeman JI, Lenfant C, et al. ACC/AHA/NHLBI clinical advisory on the use and safety of statins. Circulation 2002; 106(8): 1024-8. doi: 10.1161/01. CIR.0000032466.44170.44.
 4. Liu KD, Chertow GM. Acute renal failure. In: Braunwald E, Kaspar DL, Hauser SL, Longo DL, Jameson JL, eds. Harrison’s Principles of Internal Medicine. 17th ed. New York: McGraw-Hill; 2008. pp. 1752-61.
 5. Kokko JP. Rhabdomyolysis. In: Goldman L, Bennett JC, eds. Cecil Textbook of Medicine. 22nd ed. Philadelphia, Pa: Saunders; 2004. p. 649-51.
6. Deighan CJ, Wong KM, Mclaughlin KJ, Harden P. Rhabdomyolysis and acute renal failure resulting from alcohol and drug abuse. QJM 2000; 93(1): 29- 33.