Journal of Emergency Practice and Trauma

A case of cardiac arrest following Brugada syndrome as a rare disorder

Document Type : Case Report

Authors

Seyed Reza Habibzadeh 1
Samaneh Abiri 2
Saeed Barazandehpour 3
Mohammad Javad Zarei 4
Mahdi Foroughian 1
Hamideh Akbari 5
Navid Kalani 6, 7
Esmaeil Rayat Dost 2
Seyed Hamed Hojati 8

1 Department of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2 Department of Emergency Medicine, Jahrom University of Medical Sciences, Jahrom, Iran

3 Department of Emergency Medicine, Kerman University of Medical Sciences, Kerman, Iran

4 Department of Emergency Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

5 Department of Emergency Medicine, Tehran University of Medical Sciences, Tehran, Iran

6 Critical Care and Pain Management Research Center, Jahrom University of Medical Sciences, Jahrom, Iran

7 Research Center for Social Determinants of Health, Jahrom University of Medical Sciences, Jahrom, Iran

8 Student Research Committee, Jahrom University of Medical Sciences, Jahrom, Iran

https://doi.org/10.34172/jept.2020.03
Abstract
Objective: Brugada syndrome (BrS) is a disorder in which the electrical activity in the heart is abnormal and affects individuals with cardiac dysrhythmia. In the present study, we introduce a case diagnosed with BrS, admitted to intensive care unit (ICU) and received treatments following sudden cardiac arrest. Case Report: The patient was a male 25-year-old medical student enrolled in the sixth academic year who suffered from loss of consciousness due to sudden cardiac arrest. The patient immediately received cardiopulmonary resuscitation (CPR) measures, was visited by a cardiologist and a neurologist, and was consequently treated with medications. After an 8-day stay in the coronary care unit (CCU), the patient regained his level of consciousness and he was transferred to the ICU of Faghihi hospital in the city of Shiraz, Iran. Being diagnosed with BrS and following pulmonary aspiration treatments, he finally implanted with an implantable cardioverter defibrillator (ICD). Conclusion: Fortunately, necessary measures had been taken on time for the introduced patient and he was discharged with full recovery after 6 days

Keywords

Brugada syndrome (BrS)
Cardiac arrest
Implantable cardioverter defibrillator(ICD)
Subjects
1. Antzelevitch C, Brugada P, Borggrefe M, Brugada J, Brugada R, Corrado D, et al. Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association. Circulation 2005; 111(5): 659-70. doi: 10.1161/01.cir.0000152479.54298.51.
2. Benito B, Brugada J, Brugada R, Brugada P. Brugada Syndrome. Rev Esp Cardiol (Engl Ed) 2009; 62(11): 1297- 315. doi: 10.1016/S1885-5857(09)73357-2.
3. Khatami M, Ghanei Yakhdan Z. Novel nucleotide changes in mitochondrial COXII, cytochrome B and tRNAGlu genes in patients with Brugada syndrome. Journal of Shahid Sadoughi University of Medical Sciences 2014; 22(1): 981- 8. [In Persian].
4. Antzelevitch C, Yan GX, Ackerman MJ, Borggrefe M, Corrado D, Guo J, et al. J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge. Europace 2017; 19(4): 665-94. doi: 10.1093/ europace/euw235.
5. Moradimoghadam O, Sedaghat A, Niakan M, Hajiesmaeili MR, Seifi S, Soleimanirad R. Sudden cardiac arrest due to Brugada syndrome: a case report and literature review. Journal of Shahid Sadoughi University of Medical Sciences 2013; 21(1): 113-7. [In Persian].
6. Eftekhari H. Case study of Brugada syndrome presenting initially as acute myocardial infarction. Int Emerg Nurs 2015; 23(4): 329-33. doi: 10.1016/j.ienj.2015.02.001
 7. Sieira J, Ciconte G, Conte G, Chierchia GB, de Asmundis C, Baltogiannis G, et al. Asymptomatic Brugada syndrome: clinical characterization and long-term prognosis. Circ Arrhythm Electrophysiol 2015; 8(5): 1144-50. doi: 10.1161/ circep.114.003044.
8. Ueoka A, Morita H, Watanabe A, Nakagawa K, Nishii N, Nagase S, et al. Activation pattern of the polymorphic ventricular tachycardia and ventricular fibrillation on body surface mapping in patients with Brugada syndrome. Circ J 2016; 80(8): 1734-43. doi: 10.1253/circj.CJ-16-0124.
9. Morita H, Zipes DP, Wu J. Brugada syndrome: insights of ST elevation, arrhythmogenicity, and risk stratification from experimental observations. Heart Rhythm 2009; 6(11 Suppl): S34-43. doi: 10.1016/j.hrthm.2009.07.018.
10. Amin AS, Klemens CA, Verkerk AO, Meregalli PG, Asghari-Roodsari A, de Bakker JM, et al. Fever-triggered ventricular arrhythmias in Brugada syndrome and type 2 long-QT syndrome. Neth Heart J 2010; 18(3): 165-9. doi: 10.1007/bf03091755.
11. Matsuo K, Kurita T, Inagaki M, Kakishita M, Aihara N, Shimizu W, et al. The circadian pattern of the development of ventricular fibrillation in patients with Brugada syndrome. Eur Heart J 1999; 20(6): 465-70. doi: 10.1053/ euhj.1998.1332.
12. Mizumaki K, Fujiki A, Nishida K, Iwamoto J, Sakamoto T, Sakabe M, et al. Postprandial augmentation of bradycardiadependent ST elevation in patients with Brugada syndrome. J Cardiovasc Electrophysiol 2007; 18(8): 839-44. doi: 10.1111/j.1540-8167.2007.00872.x.
13. Mizumaki K, Fujiki A, Tsuneda T, Sakabe M, Nishida K, Sugao M, et al. Vagal activity modulates spontaneous augmentation of ST elevation in the daily life of patients with Brugada syndrome. J Cardiovasc Electrophysiol 2004; 15(6): 667-73. doi: 10.1046/j.1540-8167.2004.03601.x.
14. Kasanuki H, Ohnishi S, Ohtuka M, Matsuda N, Nirei T, Isogai R, et al. Idiopathic ventricular fibrillation induced with vagal activity in patients without obvious heart disease. Circulation 1997; 95(9): 2277-85. doi: 10.1161/01. cir.95.9.2277.
15. Noda T, Shimizu W, Taguchi A, Satomi K, Suyama K, Kurita T, et al. ST-segment elevation and ventricular fibrillation without coronary spasm by intracoronary injection of acetylcholine and/or ergonovine maleate in patients with Brugada syndrome. J Am Coll Cardiol 2002; 40(10): 1841- 7. doi: 10.1016/s0735-1097(02)02494-4.
16. Matsuo K, Shimizu W, Kurita T, Inagaki M, Aihara N, Kamakura S. Dynamic changes of 12-lead electrocardiograms in a patient with Brugada syndrome. J Cardiovasc Electrophysiol 1998; 9(5): 508-12. doi: 10.1111/ j.1540-8167.1998.tb01843.x.
17. Miyazaki T, Mitamura H, Miyoshi S, Soejima K, Aizawa Y, Ogawa S. Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome. J Am Coll Cardiol 1996; 27(5): 1061-70. doi: 10.1016/0735- 1097(95)00613-3.
Journal of Emergency Practice and Trauma
Volume 7, Issue 2
July 2021
Pages 130-132

  • Receive Date 12 January 2020
  • Revise Date 20 March 2020
  • Accept Date 22 March 2020

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