Journal of Emergency Practice and Trauma

Medical system error causing methotrexate poisoning and delay in diagnosis: report of two cases

Document Type : Case Report

Authors

Hamidreza Reihani 1
Maryam Ziadi Lotfabadi 2

1 Department of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2 Department of Emergency Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

https://doi.org/10.34172/jept.2020.24
Abstract
Objective: We are going to alert the emergency physicians to be aware of drugs side effects. Some drugs like methotrexate are not routine drugs, and the symptoms may be miss diagnosed if not completely notified.
Case Presentation: We present two patients under treatment with methotrexate. Both of them suffered from methotrexate poisoning due to improper use. We discuss the causes of methotrexate poisoning and its prevention.
Conclusion: A significant proportion of methotrexate users may not be completely aware of its proper use and the side effects. One of the important ways to prevent the toxicity of methotrexate is educating patients and their companions in order to use it correctly.

Keywords

Methotrexate toxicity
Mucocutaneous lesions
Pancytopenia
Subjects
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Journal of Emergency Practice and Trauma
Volume 7, Issue 1
January 2021
Pages 74-76

  • Receive Date 16 September 2020

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