Prognosis of emergency room stabilization of decompensated congestive heart failure with high dose lasix

Pouraghaei, Mahboob; Mohammadi, Behzad; Taghizadeh, Ali; Habibollahi, Paria; Moharamzadeh, Payman

Prognosis of emergency room stabilization of decompensated congestive heart failure with high dose lasix

Document Type : Original Article

Authors

Mahboob Pouraghaei ¹

Behzad Mohammadi ¹

Ali Taghizadeh ¹

Paria Habibollahi ²

Payman Moharamzadeh ¹

¹ Emergency Department, Tabriz University of Medical Sciences, Tabriz, Iran

² Pharmacology and Toxicology Department, Tabriz University of Medical Sciences, Tabriz, Iran

Abstract

Objective: Congestive heart failure (CHF) has become one of the most important health care problems in western countries. This article focuses on the outpatient diagnosis and management of heart failure. We want to compare the outcome of patients who were treated with high dose diuretics in the emergency department (ED) without admission with patients who were admitted to hospital for standard treatment.
Methods: This was a randomized prospective clinical trial study. The patients who came to the ED from March 20, 2008 up to August 20, 2008 were divided into two groups randomly. The length of ED stay in the experimental group was documented. Also, readmission and mortality in 6 months and satisfaction in both groups were taken into consideration. All data were analyzed using SPSS 15.0.
Results: In experimental group, the rate of recurrent admission, expiration, discharge, clinic visit, and clinic admission was 8%, 4%, 29%, 18%, and 0% respectively. On the other hand, in control group it was 16%, 40%, 18%, 22%, and 2% respectively. Additionally, there was a significant difference between these groups (P = 0.00).
Conclusion: This study is the first regional prospective trial to comprehensively examine the therapeutic management in patients with CHF. This study, comparing the high dose diuretic efficacy in the decreasing of hospital stay and readmission; and decreasing mortality rate with routine therapy, showed that there was a significant difference between these two strategies in the mortality rate, readmission, and length of hospital stay (P = 0.00).

Keywords

Aggressive therapy

Congestive heart failure

Diuretics

Subjects

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