Document Type : Case Report


1 Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

2 Rheumatology Research Center, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran

3 Department of Internal Medicine, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran


Objective: Since the identification and spread of the novel coronavirus disease 2019
(COVID-19) in December 2019, respiratory presentations have been introduced as the
main symptoms of this new type of viral disease; however, the extra-pulmonary features
are raising awareness for researchers due to the vast diversity of vital organs affected
by the virus. Among the wide range of clinical manifestations, limited data are available
regarding rhabdomyolysis (RML) in COVID-19.
Case Presentation: In this report, we present a 58-year-old woman with COVID-19
presenting with RML, with extremely elevated creatinine phosphokinase (CPK) and lactate
dehydrogenase (LDH) levels (3283 and 1280 U/L, respectively) as the second sign of
disease. Since the onset of the COVID-19 pandemic, several COVID-19 induced RML cases
have been reported, and timely diagnosis and proper management are of paramount
Conclusion: Due to the findings that rhabdomyolysis can be a critical and missed cause of
myalgia in COVID-19 patients, the importance of checking the serum level of CPK in patients
with myalgia and fatigue in the era of COVID-19 upon their arrival will be highlighted.


Main Subjects

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